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COVID-19 Vaccine Induced Thrombotic Thrombocytopenia VITT

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https://petermcculloughmd.substack.com/p/covid-19-vaccine-induced-thrombotic Recopying from his substack. Just in case it gets taken down. There are over 1000 peer-reviewed papers in the preprint server system and or in the National Library of Medicine (PUBMED) describing side effects after mRNA or adenoviral DNA COVID-19 vaccination. One of the most dreaded complications is vaccine-induced thrombotic thrombocytopenia (VITT). Because the Spike protein produced in response to the vaccine genetic code causes hemagglutination and micro blood clotting, there is excessive antigenic presentation of platelets to the spleen and reticuloendothelial system. As a result, the body produces auto-antibodies directed against a platelet receptor (PF4) which has homology with an endothelial protein. This causes autoantibody “pinning” of platelets to the lining of blood vessel cells resulting in consumption of platelets, blood clotting and bleeding at the same time. Unfortunate victims are fin...
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VITT is currently termed 'thrombosis with thrombocytopenia syndrome (TTS)' by the Centers for Disease Control and Prevention (CDC) and the US Food and Drug Administration (FDA)

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Interesting. That's all. https://www.spandidos-publications.com/10.3892/ijmm.2022.5090
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Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia VITT

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Thrombocytopenia in COVID‑19 and vaccine‑induced thrombotic thrombocytopenia Full paper: https://www.spandidos-publications.com/10.3892/ijmm.2022.5090 https://pubmed.ncbi.nlm.nih.gov/35059730/ uthors: Styliani A. Geronikolou Işil Takan Athanasia Pavlopoulou Marina Mantzourani George P. Chrousos View Affiliations Published online on: January 21, 2022 https://doi.org/10.3892/ijmm.2022.5090 Article Number: 35 Copyright: © Geronikolou et al. This is an open access article distributed under the terms of Creative Commons Attribution License. Metrics: Total Views: 3287 (Spandidos Publications: 3287 | PMC Statistics: 0 ) Total PDF Downloads: 1315 (Spandidos Publications: 1315 | PMC Statistics: 0 ) Cited By (CrossRef): 2 citations View Articles 22 total citations on Dimensions. 2 Total citations 2 Recent citations n/a Field Citation Ratio n/a Relative Citation Ratio Article has an altmetric score of 2 See more details Tweeted by 2 42 readers on Mendeley Abstract The highly heterogene...
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Influence of Thrombocytopenia on the Outcome of Mechanical Thrombectomy in Patients with Acute Ischemic Stroke

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https://pubmed.ncbi.nlm.nih.gov/34915307/ Influence of Thrombocytopenia on the Outcome of Mechanical Thrombectomy in Patients with Acute Ischemic Stroke Mirjana Ždraljević 1, Tatjana Pekmezović 2, Predrag Stanarčević 3, Ivan Vukašinović 4, Ivana Berisavac 3, Marko Ercegovac 3, Filip Vitošević 4, Dragoslav Nestorović 4, Vladimir Cvetić 5, Višnja Padjen 3, Maja Stefanović- Budimkić 1, Tamara Švabić Medjedović 1, Dejana R Jovanović 6 Affiliations expand PMID: 34915307 DOI: 10.1016/j.jstrokecerebrovasdis.2021.106240 Abstract Objectives: Mechanical thrombectomy (MT) has become leading treatment option for acute ischemic stroke (AIS) due to large vessels occlusion (LVO). Platelet counts may affect outcome in patients with AIS or transient ischemic attack. The aim of our study was to determine the influence of thrombocytopenia on the safety and efficacy of MT in patients with AIS due to anterior circulation LVO. Materials and methods: This study included 127 consecutive adult patients with...
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Pennsylvania Senator Suffers Stroke Requiring Thrombectomy

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https://gab.com/SharylAttkisson/posts/108971571577122014 Definition: MT Mechanical thrombectomy, or simply thrombectomy, is the interventional procedure of removing a blood clot from a blood vessel. It is commonly performed in the cerebral arteries. The effectiveness of thrombectomy was confirmed in several randomised clinical trials conducted at various medical centers throughout the United States
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SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia

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LINK to Paper SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Tracking no: ADV-2021-005050R2 Jacob Appelbaum (University of Washington School of Medicine, United States) Donald Arnold (McMaster University, Canada) John Kelton (McMaster University, Canada) Terry Gernsheimer (University of Washington School of Medicine, United States) Stefan Jevtic (McMaster University, Canada) Nikola Ivetic (McMaster University, ) James Smith (McMaster University, Canada) Ishac Nazy (McMaster University, Canada) Abstract: Conflict of interest: No COI declared COI notes: Preprint server: No; Author contributions and disclosures: J Appelbaum provided clinical care of the patient, analyzed and interpreted data and wrote the manuscript. D.M. Arnold designed the research and wrote the manuscript. J.G. Kelton designed the research and wrote the manuscript. T. Gernsheimer provided clinical care of the patient, analyzed and interpreted data and wrote the manusc...
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Vaccines against Covid-19, venous thromboembolism, and thrombocytopenia. A population-based retrospective cohort study

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https://www.medrxiv.org/content/10.1101/2021.07.23.21261036v1 Abstract Background  Covid-19 vaccines may increase the risk of venous thromboembolism (VTE), thrombocytopenia (TCP), and VTE associated with TCP. We aimed at estimating this risk by age and sex, after the first dose of both adenovirus vector-based and mRNA-based Covid-19 vaccines, and after the second dose of m-RNA vaccines. Methods  In this population-based retrospective cohort study, we examined three groups: 1 662 719 people 10 years of age and over vaccinated with the first dose of a Covid-19 vaccine, 622 778 with the second dose, and 190 616 diagnosed of Covid-19 in the same period (between1 January 2021 and 18 April 2021). The rates of various clinical presentations of VTE and TCP were compared with those in the reference population (7 013 040 people served by the health care system in 2919). The two primary outcomes were the observed 21 day rate of a composite variable of cerebral venous sinus thrombosis, m...
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